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Will SYNDROS Potential Replace SUBSYS Challenges

Insys has been the subject of negative publicity as state and federal investigations continue against six ex-employees regarding the sales and billing practices of the company in the past. The investigations surround the company’s drug, Subsys, a fentanyl-based sublingual spray used for the treatment of cancer patients.

Insys issued a response to recent media reports by reiterating its commitment towards the highest ethical standards and compliance with all its activities and business practices and complying with governing laws and regulations and cooperating with relevant governmental authorities in ongoing investigations. Management also highlighted that Insys intends to play a meaningful role in providing solutions to address the opioid epidemic by developing innovative products. These potential product solutions include cannabidiol (a novel, non-opioid) for the treatment of opioid dependence, for the treatment of pain and naloxone nasal spray for the treatment of opioid overdose.

Will INSYS continue with SUBSYS, what the analysts say and Q1 review: READ MORE.

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On the brighter side, FDA approved the final labeling for Syndros (dronabinol oral solution, a pharmaceutical version of THC), which may classify the drug as a Schedule II controlled substance. Insys expects to launch the product in August 2017. Syndros is indicated for the treatment of anorexia associated with weight loss in patients with AIDS and in the treatment of nausea and vomiting associated with cancer chemotherapy in patients who have failed to respond adequately to conventional antiemetic treatments. Syndros will be a direct competitor to Marinol, a product offered by Abbvie in pill form. Since Syndros is a liquid, it should be easier to swallow and can be administered in prescribed dosages. Dronabinol was approved by the FDA decades ago as a treatment option for cancer patients. Today, the potential applications for dronabinol, including sleep apnea and opioid dependency, could catapult this drug to annual sales in the billions.

Details of SYNDROS development and its potential: READ MORE.

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