Cannabis Researchers Find the Reasons for Cannabis Tolerance

The most recent research from marijuana researchers shows the reason behind the tolerance for marijuana and shows us that it does not take much time for the brain to go back to normal after smoking. A newly published study by Deepak Cyril D’Souza et al, a renowned marijuana scientist from the Yale School of Medicine, has suggested how a tolerance to marijuana occurs, and approximately how long it takes for it to get back to normalcy.

This newest piece of research was a project worked on between various prestigious organizations. For instance, here is a list of some of the organizations that took part in the study: Schizophrenia and Neuropharmacology Research Group of the Connecticut Healthcare System, Yale University School of Medicine, the New York University Langone Medical Center and the Harvard Medical School Massachusetts General Hospital.

The classic issue with marijuana calls for people to consume more for the first time. Unlike other drugs, overdosing on marijuana is extremely unlikely, and THC does not become dangerous until its levels become insanely high. For instance, you’d have to eat points of the psychoactive ingredient in just one sitting. Though a pothead might need to smoke successively more pot as time goes on, it does not ever become anything crazy; someone could consume the same amount of pot every day for the rest of his or her life and still get high.

The research used males from the ages of 18 to 35 that were “cannabis dependent,” as indicated by the Diagnostics and Statistics Manual-IV. “They used positron emission tomography (a PET scan) to observe a radiotracer ligand for cannabinoid receptor 1 (CB1), the receptor in our brains triggered by THC in cannabis to induce its psychoactive effects.” The PET was able to detect where exactly CB1 receptors are found in the brain and how scattered they were throughout each portion.