Marijuana Stocks Face A Major Regulatory Catalyst That Could Help Trading
More than ever, federal cannabis reform is gaining momentum. With all the progress that has evolved since mid-2018, the future holds untapped potential. But the big issue remains: there is no true federal reform, even with the recent rescheduling of cannabis to a now class 3 subtance. For those invested in the sector, this regulatory progress could continue creating volatility across marijuana stocks and pot stocks. Schedule III treatment may eventually improve research opportunities and significantly change the tax environment for qualifying cannabis businesses.
Under current federal rules, Section 280E prevents businesses trafficking in Schedule I or II substances from deducting many ordinary operating expenses. Until the applicable legal changes take effect, investors should avoid treating potential tax relief as guaranteed or immediate. Regulatory momentum has the ability to lift cannabis stocks quickly.
Yet often sustainable performance will still depend on company fundamentals and overall progress. As 2027 rapidly approaches, now is a good time to learn which marijuana stocks to buy that offer the best upside towards future gains. The cannabis industry is still growing, so there is more to be seen and done that can ultimately lead to stronger company performance in the market. Below are several top marijuana stocks to watch during the month of September.
Top Marijuana Stocks For You Today
Trulieve Cannabis Corp.(NYSE:TRLV)
Green Thumb Industries Inc.(OTC:GTBIF)
Cresco Labs Inc.(OTC:CRLBF)
Trulieve Cannabis Corp.
Trulieve Cannabis Corp. is one of the largest vertically integrated cannabis companies in the United States. The company cultivates, manufactures, and sells its own products through a network of 207 dispensaries, with major operations in Florida, Georgia, Pennsylvania, and West Virginia. Its scale and strong position in medical marijuana make Trulieve an important company for investors following U.S. cannabis stocks.
Recent results present a mixed but encouraging picture. Trulieve reported second-quarter 2026 revenue of $271 million, down 10% year over year, while maintaining a strong 60% gross margin. The company generated $53 million in operating cash flow and $32 million in free cash flow during the quarter. Although it recorded a $406 million GAAP net loss, approximately $407 million was connected to the deconsolidation of Harvest and related accounting adjustments. Excluding certain nonrecurring items, adjusted net income was $20 million.
Green Thumb Industries Inc.
Green Thumb Industries Inc. is a major U.S. cannabis consumer-products company and multistate retailer. It sells brands such as RYTHM, Dogwalkers, Incredibles, and Good Green while operating more than 120 RISE dispensaries across 14 markets. This combination gives investors exposure to both branded cannabis products and retail sales. Recent expansion includes new RISE dispensaries in Florida, Pennsylvania, and Nevada. 
Green Thumb could also benefit from Virginia’s planned adult-use market launch in 2027, where it already holds a vertically integrated medical license. For long-term investors, GTBIF stock stands out for its positive earnings, cash generation, and measured expansion. Its ability to protect margins while growing in newer markets will be more important than short-term movement in marijuana stocks.
[Read More] Top U.S. Marijuana Stocks to Watch as Cannabis Reform Gains Momentum
Cresco Labs Inc.
Cresco Labs Inc. is a vertically integrated U.S. cannabis company that trades over-the-counter as CRLBF. It produces nationally recognized brands—including Cresco, High Supply, FloraCal and Good News—and operates dispensaries under the Sunnyside name. Unlike companies primarily focused on retail, Cresco also has a significant wholesale business, giving investors exposure to branded products sold through third-party dispensaries. Recent news includes the $50 million acquisition of nine Pennsylvania dispensaries. 
This strengthens Cresco’s position in one of the country’s largest medical marijuana markets. The company is also expanding in Ohio and introducing branded products in Kentucky. For investors, Cresco offers established cannabis brands, improving quarterly performance and strategic expansion.
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The risks include approximately $330 million in secured and mortgage debt versus $67 million in cash. These include considerable interest expense, regulatory uncertainty, and an ongoing chief financial officer transition.
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